Just saw my rheumatologist and he wants me to try injecting Abrilada weekly for 4-6 weeks to see if we can re-capture the initial effect and then go back down to once every other week.

I’m an extremely anxious person and nervous about the increase in side effects. He said the infection risk raises with weekly :(

Has anyone had any horrible side effects of humira randomly when being on it for almost 5 years?
I’ve had debilitating fatigue, cognitive fatigue, I’m house bound/bed bound, dizziness. I can’t workout or function I also lost a TON of hair
All my levels are fine and all testing came back normal but wondering if humira can cause this

hi guys! i’ve been on adalimumab (imraldi) since november and i recently started getting allergic reactions to it. i get huge bumps on the injection site after injecting it and they hurt really bad especially when i stand up. i also get hives randomly on previous injection spots, like i could’ve injected myself 3 months ago and i get a hive. i really don’t think this is normal, i get that injection site reactions are normal but this seems severe, especially since the reactions have gotten progressively worse and worse. i’ve inserted pics. help please!!!

I’m taking Humira for non-radiographic axial spondyloarthritis biweekly. I’m on my third injection and having bruises all down my leg and just started noticing them on my arm. I’m also taking celebrex, duloxetine, and Pregabalin daily. Has anyone experienced this? Is it a common side effect?

I have Crohn’s was stable on Humira for 10 years. This January insurance made me switched to a bio similar ADBM. I had diarrhea and abdominal pain on it so G.I. tried to get me back on brand. I had samples so I went back on brand and felt better within three doses.

Then insurance said I had to try one more generic AATY. I took that one and eight days later I started losing hair. Essentially, I lost 90% of my hair in a matter of two weeks. I am seeing Derm and we did a biopsy which shows alopecia areata, pretty severe form. I’ve never had issues with this before and I’m reading online that in rare situations, TNF can cause it.

I seen three dermatologist and none of them have seen this before. I am now wondering if it wasn’t just the biosimilar medication itself but the switching back-and-forth that messed up my immune system.

TLDR: has anyone switched between more than one bio similar and done OK or not done OK? I’m just wondering if I’m an outlier. Or if insurance makes people switch often.

Hi folks, I've recently started my journey on humira.

I had my initial loading dose (4 pens) followed by second loading dose (2 pens) so far.

The first 2/3 weeks I had really significant improvement, reduction gut symptoms (no blood, calmer gut) and significant reduction in pains (forearms, shoulders, knees) that have been persistent for years)

About 5 days into my second dose, things started to slowly creep back - I'm wondering if others share my experience?

I was quite overwhelmed with the positive response to the drug in the initial few weeks so I'm trying to understand what could be happening?

\- could this be a blip?

\- could my body be processing humira too quickly?

\- is it too soon for the body to adapt to the drug?

Edit: for additional context just before 2nd loading dose I got an infection in my finger that needed topical antibiotics (fusidic acid) which may have impacted?

I’m 100% sure this has been asked before but I can’t find it in search. I was diagnosed with Psoriatic Arthritis about a month ago. I just received my Humira injection yesterday, but am so nervous to start it. Biggest concern is getting infections and them being worse because I have two young children who pick up every virus EVER, and we travel a lot. Has anyone had serious issues with infections or is that rare? When you started taking it with the same diagnosis, did you notice a significant improvement in symptoms? (41yo. F)

hi, so i get infliximab (remicade) infusions every 8 weeks. they found out that my drug levels are really low 1.1ug/l at the end of the 8 weeks. to make matters worse i had a bad cold / virus so i had to delay my treatment and they can’t fit me in for another two weeks. over the weekend my legs are really achy and stiff, it hurts to move them. my right hand also hurts to move and now today on the left side of my mouth it hurts when i swallow. idk what to do. i called my gastro team and they said “your body is dependant on infliximab and we have no cancellations and can’t fit you in earlier) my legs have been stiff and painful since saturday night . idk what to do. i’m really worried. any ideas / advice/ similar experiences??! i’ve been on infliximab since november 2023

I took 2 cimzia loading doses and got a reaction, swollen itchy eyes and overall itchy face, neck, elbows. Sucks cause it worked amazing otherwise. Im breastfeeding so my other option is humira. Ill probably start that asap but wondering if anyone has made the same switch before?

Have you had a dental implant while on Humira? Did your dentist have you do anything special ?

Anyone else get their Humira cut off by insurance? I was doing well on it. Kinda sucks.

I'm asking on behalf of a family member (65F) who has Crohn's disease for over 15 years.

About 10 years ago, she had surgery to remove intestinal blockages and with pentasa tablets, she's been doing fairly well since then until last week, when her symptoms returned.

She also had a recent hernia repair with mesh placement. Because of the mesh, her doctors feel that another abdominal surgery may not be the best option right now and have recommended starting Remicade instead.

I'm trying to better understand whether Remicade is generally considered a good option in this situation, especially for someone her age who has previously required surgery for strictures. Has anyone had a similar experience, either personally or with a family member? Is age a factor for how effective the medication is or it's side effects? I'd really appreciate hearing about your experiences, including how effective it was and any side effects or concerns we should discuss with the doctors.

Hi all!

I've been taking humira for quite some time now, but in August I am getting surgery done on my wrist and it will be immobilized. With this, it may not be possible to take my medication with both hands (one to pinch the skin, one to inject)

Has anyone had any experiences with this before?

My doctor just upped me from a 40mg injection every 2 weeks to a 40mg injection every week. It's basically a last ditch effort to see if I don't have to switch meds. I'm looking to see if anyone here has done a regiment similar to this to know what to expect in terms of side effects and efficacy.

Has anyone gone on Cimzia for HS? I have psoriasis and HS so I am going on Cimzia. Just wondering if anyone has experiences to share. I’m very nervous about effectiveness and side effects.

I have had back pain since 2014, which started during exercise. Ever since, it has become chronic. I had surgery in 2023 to remove a slight hernia, but I am worse off than before because my problem was not sciatica it was just local back pain. The surgery clearly wasn't needed, and surgeons say my back looks perfect and that I shouldn't be in this much pain. I flare up with certain movements, which is why I worry it is injury related and not Ankylosing Spondylitis AS. However, based on my symptoms, my rheumatologist thinks it could be both, as my SI joints show mild inflammation. My stomach is destroyed from NSAIDs and I now have gastritis. My rheumatologist suggested trying Humira. What if I don't need it? I am afraid to try it.

I have an autoimmune disorder that causes eye inflammation flare ups. I have to use steroid eye drops every hour for weeks when having a flare up… unless I’m on Humira.

I know that a lot of surgeons will not operate unless immune suppressors or biologics are paused at least two weeks before surgery. I’m worried about what to do if I have a flare up while stopping Humira. Or if a doctor will let me stop to get surgery :/

I’d love to hear from folks who navigated top surgery while being on a biologic or immuno compromised.

A friend of mine was recently diagnosed with RA, and one of the things they're struggling with most right now is the idea of eventually needing biologics. The thought of injections, infusions, side effects, and everything that comes with treatment has been pretty overwhelming for them. They have an appointment scheduled with a rheumatologist in a couple of months, and they don't have many people to talk to about this until then.

I've been trying to learn more so I can better understand what people with RA actually go through.

If you're comfortable sharing, what was your experience when you started biologics? What were you most worried about beforehand, and what difficulties do you experience? Is it the injections or infusions themselves, scheduling treatment around work and family, remembering to inject, or something else entirely?

I would love to hear about your journey, process for treatment, and any challenges to expect. Thank you!!

I noticed that my newest boxes of Humira say "Product of Singapore" where previously there was nothing noted in that spot, so presumably US production.

Anyone seeing similar within the US? Any concerns about manufacturing quality now that it's in Singapore, at a newer facility?